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--- rabies-data [2023/05/02 03:42] – kc
+++ rabies-data [2023/05/02 10:22] (current) – kc
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 [[https://medilib.ir/uptodate/show/8322]]
-"Well documented
+"Well-documented incubation periods may vary from ten days to six years." page12 of [[https://mro.massey.ac.nz/bitstream/handle/10179/4545/02_whole.pdf]]
+"Incubation time
+"The incubation time was documented in 47/60 records (Figure 3) with a mean incubation time of 273.6 days
+(median time: 80 days, range, 12–3600 days), including nine cases with an incubation time of 30 days or less.
+ Very short incubation times were observed in two cases. A 50-year-old French female tourist sustained
+multiple deep dog bites on the legs during a trip in India and developed rabies 12 days later while
+returning to France [9], [10]. A 19-year-old male Mexican seasonal worker was bitten by a bat on his leg
+and developed rabies due to a variant virus of vampire bat rabies 15 days later in the US [7], [8].
+In three cases, very long incubation times were recorded. A 10-year-old female migrant from Vietnam who
+stayed 1.5 years in Hong Kong prior to immigrating to Australia developed rabies more than five years after
+she had lived continuously in Australia. The sequence of the rabies virus isolated post-mortem was closely
+related to a subgroup of viruses found in China. No history of animal bites was documented [11]–[13].
+A 40-year-old man developed rabies in the US due to a canine rabies virus variant associated with dogs in
+Brazil, which was identified by sequence analysis of viral amplicons. After the diagnosis was established,
+interviews with family members indicated a history of contact with a “rabid-acting” dog while living in
+Brazil, approximately 8 years prior to becoming ill. An investigation of the patient's travel history did
+not identify any intermittent travel to Brazil since that time [14]. An 18-year-old male recent migrant,
+originating from Myanmar, developed rabies in Thailand. He gave a history of dog bites 10 years before,
+and he denied any recent animal bites or contact with bats [15]."
+[[https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0002209|source]]